Molecular features of human bocavirus from infantile diarrhea in Suzhou area, Jiangsu province in 2010-2011.
- Author:
Jian-guang FU
1
;
Cui-lian JIANG
2
;
Yuan-fang QIN
1
;
Jing AI
1
;
Cheng LIU
3
;
Bin WU
1
;
Xian QI
1
;
Chang-jun BAO
1
;
Ye-fei ZHU
1
;
Fen-yang TANG
4
Author Information
- Publication Type:Journal Article
- MeSH: China; epidemiology; Diarrhea, Infantile; epidemiology; virology; Female; Genotype; Human bocavirus; genetics; isolation & purification; Humans; Infant; Male; Phylogeny; Sequence Analysis, DNA
- From: Chinese Journal of Epidemiology 2013;34(12):1216-1218
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the status of human bocavirus and to identify its epidemiological characteristics as well as genotype distribution in patients with infantile viral diarrhea in Suzhou, Jiangsu province.
METHODS832 fecal specimens from patients with infantile virus diarrhea cases were collected from Suzhou Children's Hospital in 2010-2011. Human bocavirus were detected by Real-Time RT-PCR, and genotype were determined by sequence analysis.
RESULTSAmong all the fecal specimens, 51 (6.1%) cases were positive for human bocavirus. The peak season of rotavirus infection was between July and September. Of all the episodes on rotavirus diarrhea, 96% occurred before 2 years of age, with peaks in children with 7-12 months of age. Data from Nucleotide Sequence analysis showed that among 28 samples that carrying HBoV-1, 5 strains belonged to HBoV-2, HBoV type 3 but type 4 were absent.
CONCLUSIONHuman bocavirus were detected from fecal specimens of infantile virus diarrhea in Suzhou, with genotype HBoV-1 as the major strain. HBoV-2 genotype was also found.