Study on the adherence and related determinants among HIV-positive clients under methadone maintenance treatment in Dali,Yunnan province from 2005 to 2013.

Haibo Jiang; Xiaobin Cao; Changhe Wang; Wei Luo; Jianhua LI; Keming Rou; Bo Zhang; Yuehua Fang; Cong LI; Zunyou WU

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Study on the adherence and related determinants among HIV-positive clients under methadone maintenance treatment in Dali,Yunnan province from 2005 to 2013.

Author: Haibo JIANG ^{1
,

2} ; Xiaobin CAO ³ ; Changhe WANG ³ ; Wei LUO ³ ; Jianhua LI ⁴ ; Keming ROU ³ ; Bo ZHANG ⁴ ; Yuehua FANG ⁵ ; Cong LI ⁶ ; Zunyou WU ¹ ;
Author Information

1. School of Public Health, Anhui Medical University, Hefei 230032, China
2. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention.
3. National Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention.
4. Yunnan Institute for Drug Abuse.
5. Dali City Center for Disease Control and Prevention.
6. Dali Prefecture No. 2nd People's Hospital.
Publication Type:Journal Article
MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Antiretroviral Therapy, Highly Active; Child; Child, Preschool; China; epidemiology; Female; HIV Infections; drug therapy; epidemiology; psychology; HIV Seropositivity; Humans; Male; Medication Adherence; Methadone; therapeutic use; Middle Aged
From: Chinese Journal of Epidemiology 2014;35(3):255-258
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo describe the adherence and related determinants among HIV-positive methadone maintenance treatment(MMT)clients in Dali,Yunnan province from 2005 to 2013.
METHODSCases were selected from the "National MMT Information Management System". The main information included demographic, drug abuse behaviors prior to enrollment, MMT treatment and highly active antiretroviral therapy (HAART). Detailed medication records were collected to calculate the adherence to MMT. Multivariate unconditional logistic regression was conducted to analyze the impact factors of adherence.
RESULTSThe MMT adherence rate of 480 subjects is 58.11%. Data from the multivariate unconditional logistic regression indicated that among those HIV-positive MMT clients that on HAART program (OR = 1.52, 95% CI:1.03-2.24), related factors as:having stable job(OR = 1.69, 95% CI:1.11-2.56), having compulsory history prior to enrollment in MMT (OR = 1.78, 95% CI:1.04-3.04) were likely to have higher rate on MMT adherence, whereas clients who showed positive result in the last urine morphine test (OR = 0.38, 95% CI:0.24-0.59) were associated with lower rate on MMT adherence.
CONCLUSIONIn order to improve the rate of adherence to MMT among those HIV-positive MMT clients, the coverage of HAART needed to be expanded and new approaches in combining MMT and HAART developed. Education and intervention efforts should be focused on clients who currently were jobless, those with last urine morphine testing as positive or had never received compulsory treatment.