Clinical analysis of combined organ resection for T4b gastric cancer.
- Author:
Ming-zhi CAI
1
;
Han LIANG
;
Xiao-na WANG
;
Li ZHANG
;
Liang-liang WU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Female; Follow-Up Studies; Gastrectomy; Humans; Lymph Node Excision; Male; Middle Aged; Prognosis; Retrospective Studies; Stomach Neoplasms; surgery; Treatment Outcome
- From: Chinese Journal of Gastrointestinal Surgery 2012;15(5):502-504
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the outcomes of combined organ resection for T4b gastric cancer, and determine the operative indication and prognostic factors.
METHODSClinical data of 96 cases with T4bN0-3bM0 gastric cancer treated with combined organ resection in Tianjin Cancer Hospital from 2001 to 2005 were analyzed retrospectively.
RESULTSTwelve patients developed postoperative complications, including pancreatic fistula (n=4), abdominal infection(n=5), pulmonary infection(n=3), all of which were managed with conservative treatment. There were no perioperative deaths. All the patients had postoperative follow up with a median of 73 months. The 1-, 3-, 5-year overall survival rates were 70.5%, 42.1%, and 23.5%, respectively. Univariate analysis showed that Borrmann type, histologic type, lymph node staging, and pancreatic invasion were associated with the survival in patients with T4b gastric cancer(both P<0.05). Multivariable analysis showed that lymph node staging and histologic type were independent prognostic factors(all P<0.05).
CONCLUSIONFor well differentiated gastric cancer with lymph node staging of pN0 or pN1, combined organ resection may offer survival benefit.
