Chemical constituents of Poria cocos.
- Author:
Peng-Fei YANG
;
Chao LIU
;
Hong-Qing WANG
;
Jia-Chun LI
;
Zhen-Zhong WANG
;
Wei XIAO
;
Ruo-Yun CHEN
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
Organic Chemicals;
analysis;
Poria;
chemistry
- From:
China Journal of Chinese Materia Medica
2014;39(6):1030-1033
- CountryChina
- Language:Chinese
-
Abstract:
The chemical constituents of Poria cocos were studied by means of silica gel, ODS column chromatography, Sephadex LH-20 and preparative HPLC. Thirteen compounds were isolated from this plant. By analysis of the ESI-MS and NMR data, the structures of these compounds were determined as tumulosic acid (1), dehydrotumulosic acid (2), 3beta, 5alpha-dihydroxy-ergosta-7, 22-dien-6-one (3), 3beta, 5alpha, 9alpha-trihydroxy-ergosta-7, 22-diene -6-one (4), ergosta-7, 22-diene-3-one (5), 6, 9-epoxy-ergosta-7,22-diene-3-ol (6), ergosta-4,22-diene-3-one (7), 3beta, 5alpha, 6beta-trihydroxyl-ergosta-7,22-diene (8), ergosta-5, 6-epoxy-7,22-dien-3-ol (9), beta-sitosterol (10), ribitol (11), mannitol (12), and oleanic acid 3-O-acetate (13), respectively. Compounds 3-13 were isolated from the P. cocos for the first time.
