Analysis of multicomponent drug metabolism used in clinical pharmacy research of traditional Chinese medicine.
- Author:
Yang LIU
;
Bao-Sheng ZHAO
;
Jing-Juan WANG
;
Qiao-Hong DENG
;
Guo-Peng WANG
;
Lei ZHANG
;
Jia-Mei XIANG
- Publication Type:Journal Article
- MeSH:
Biomedical Research;
Drug Combinations;
Drug Therapy;
Drugs, Chinese Herbal;
chemistry;
metabolism;
pharmacokinetics;
Humans;
Medicine, Chinese Traditional
- From:
China Journal of Chinese Materia Medica
2014;39(7):1335-1338
- CountryChina
- Language:Chinese
-
Abstract:
Multicomponent drug metabolism can be defined as a research area that, rather than pharmacokinetics and pharmacodynamics, is a concerted dynamic metabolic variation of one component in several other compounds circumstance with the interaction of transport protein and drug metabolizing enzymes, and the study of the dynamic course of multiple components must be simultaneously determined. By the use of multicomponent drug metabolism in the clinical pharmacy research of traditional Chinese medicine (TCM), it can become a useful tool with the integration of the overall dialectical method and the concrete molecular approach.
