Evaluation of drug release behavior in vitro of ginkgolides component drug release unit.
- Author:
Dan LIU
;
Zhen-Hai ZHANG
;
Xiao-Yun CHEN
;
Xiao-Bin JIA
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
Ginkgolides;
chemistry;
Kinetics;
Solubility
- From:
China Journal of Chinese Materia Medica
2014;39(8):1426-1429
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine (TCM) composition is a multi-component multiple drug release system and more components preparation system. How to evaluate the drug release behavior of diversification has been a block for the modernization of TCM. This article through to study of more representative components of ginkgolides drug release and similarity analysis of more representative components of ginkgolides drug release behavior and use Weight coefficient method to integrate the multicomponent drug release curve. So it can provide the idea and method for drug evaluation of TCM component preparation.