Predictive value of immunological parameters on sepsis following abdominal operation for patients with HIV infection.
- Author:
Xian-jun XIA
1
;
Bao-chi LIU
Author Information
- Publication Type:Journal Article
- MeSH: Abdomen; surgery; Adult; Aged; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; immunology; Female; HIV Infections; complications; immunology; Humans; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Sepsis; etiology; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2011;14(7):500-502
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study postoperative sepsis in HIV/AIDS patients who underwent abdominal operations.
METHODSA retrospective analysis was performed to study 34 HIV/AIDS patients treated between January 2009 and December 2010 at the Shanghai Public Health Clinical Center Affiliated to Fudan University.
RESULTSThere were 31 males and 3 females in this cohort with a mean age of 45±13 years. Nineteen patients developed postoperative sepsis. The levels of preoperative CD4, postoperative CD4, preoperative CD4/CD8, and postoperative platelet were significantly lower than those without sepsis (all P<0.05). Among 19 patients with a preoperative CD4 cell count less than or equal to 200×10(6)/L, the incidence of postoperative sepsis rate was 84.2%(16/19), and for those with a preoperative CD4 cell count greater than 200×10(6)/L, the incidence of postoperative sepsis rate was 20.0%(3/15), the difference was statistically significant(P<0.05). There were 3 postoperative deaths.
CONCLUSIONCD4 cell count can be used as a predictive marker for the development of postoperative sepsis in patients with HIV/AIDS.
