A novel translocation t(1;18)(p31;p11) in a patient with myelodysplastic syndrome.
- Author:
Bing DU
1
;
Ya-fang WU
;
Jin-lan PAN
;
Yong-quan XUE
Author Information
- Publication Type:Case Reports
- MeSH: Adult; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 18; Humans; In Situ Hybridization, Fluorescence; Karyotyping; Male; Myelodysplastic Syndromes; genetics; Translocation, Genetic; genetics
- From: Chinese Journal of Medical Genetics 2005;22(1):74-75
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo report a case of myelodysplastic syndrome(MDS) with t(1;18)(p31;p11).
METHODSChromosome specimens were prepared by short-term culture of bone marrow cells. Karyotype analysis was made by R banding technique. Chromosome painting was performed using whole chromosome probes 1 and 18.
RESULTSConventional karyotype analysis revealed t(1;18)(p31;p11) in this patient. Chromosome painting analysis confirmed this result.
CONCLUSIONThe translocation of (1;18) was an unusual recurrent chromosome change and was reported on MDS for the first time.
