Metabolic syndrome and chronic kidney disease in a rural adult population of Hunan province,China
10.3760/cma.j.issn.0254-6450.2009.12.002
- VernacularTitle:湖南省某乡村成年人群中代谢综合征与慢性肾脏病的关系
- Keywords:
Metabolic syndrome;
Kidney disease;
chronic;
Screening
- From:
Chinese Journal of Epidemiology
2009;30(12):1221-1225
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between metabolic syndrome and chronic kidney disease(CKD)in a rural adult population of Hunan province.Methods 1953 residents (older than 18 years)from the same village were randomly selected,using a stratified,multistage sampling method.All residents were interviewed and tested for albuminuria with morning spot urine albumin to creatinine ratio(abnormal:≥30 mg/g),reduced renal function with estimated glomerular filtration rate by modified MDRD equation[abnormal:＜60 ml/min(1.73 m2)].The associations of kidney damage indicators with demographic characteristics(age,gender,smoking status),indicators on health(diabetes,hypertension)and metabolic syndrome traits were examined.Results Eligible data of 1709 subjects were enrolled in the study.After the adjustment of age,gender and other metabolic syndrome traits,participants with metabolic syndrome had a higher prevalence of CKD(19.3% vs.13.2%,P＜0.001)than those without the syndrome.As the number of metabolic syndrome traits increased,so did the prevalence of CKD.There seemed to be a strong and independent association between metabolic syndrome and chronic kidney disease.For participants without hypertension and diabetes,metabolic syndrome was also associated with CKD(OR value 1.733,95% CI:1.20-2.41,P=0.004).Conclusion In these 1709 adults under this study from a village of southern China,metabolic syndrome seemed to be associated with CKD.
