Establishment of animal model with gastric hot syndrome.
- Author:
Wan-bin YANG
;
Bin WEN
;
Ling-hang ZHANG
;
Hong LIU
- Publication Type:Journal Article
- MeSH:
Animals;
Disease Models, Animal;
Drugs, Chinese Herbal;
administration & dosage;
Eating;
Female;
Humans;
Male;
Rats;
Rats, Wistar;
Stomach Diseases;
drug therapy;
pathology;
physiopathology
- From:
China Journal of Chinese Materia Medica
2015;40(18):3644-3649
- CountryChina
- Language:Chinese
-
Abstract:
This study is to establish the gastric hot model of rats. After gastric feeding with ethanol solution for 3 weeks and feeding with extra capsaicin and ethanol solution for another 2 weeks, model group show distinct physical sign of gastric hot syndrome. The pathology of gastrics reveals gastricism of model group, while treatment group (treat with Zuojin Wan) shows mild lesion. Elisa detection of model group show that the solution of interleukin-2 (IL-2) is higher than the blank group. The obvious difference among model group, treatment group and blank group reveals the success of the establishment of gastric hot model.
