Studies on chemical constituents of Valeriana plants and their biological activities.
- Author:
Ru-Jing WANG
1
;
Qing HUANG
1
;
Yan YONG
1
;
Hong-Xiang LI
1
;
Shi-Jing ZHANG
1
;
Bao-Hua CHEN
2
;
Li-Xia ZHU
1
;
Yin CHEN
1
;
Xin TANG
1
;
Shan-Shan SONG
1
;
Xiao-Ping DONG
1
;
Yu-Zhu TAN
1
;
Hai ZHANG
1
Author Information
- Publication Type:Journal Article
- Keywords: Valeriana; chemical components; pharmacological activities
- From: China Journal of Chinese Materia Medica 2016;41(8):1405-1414
- CountryChina
- Language:Chinese
- Abstract: The recent progresses on chemical components and pharmacological activities of the genus Valerianawere summarized.Besides-essential oil, the chemical composition of Valerianais mainly focused on monoterpenoids,sesquiterpenoids,lignans, flavonoids, alkaloids, etc. Iridoids are the main chemical components ofmonoterpenoids. There are two types ofiridoidson the basis of the cyclopentane open or not. The Valerianahas been drawmuch attention for their significant sedation,spasmolysis,antidepression,antitumor, against adenosine A1 receptors and cytotoxicityactivity,and had certain function for cardiovascular disease treatment. Given to the fact of the lack of systematic review and summary of studies on the Valeriana, we summarized and analyze the study literatures on the pharmacological activity of Valerianain recent years, and providedsome basisfor further study.
