Effect of rat intestinal flora in vitro on metabolites of acteoside.
- Author:
Wen-Xiu ZHANG
1
;
Biao YANG
1
;
Yu-Mei HU
1
;
Zhao-Qing MENG
1
;
Wen-Zhe HUANG
1
;
Zhen-Zhong WANG
1
;
Wei XIAO
1
Author Information
- Publication Type:Journal Article
- Keywords: LC-MS; acteoside; intestinal flora; metabolites
- From: China Journal of Chinese Materia Medica 2016;41(8):1541-1545
- CountryChina
- Language:Chinese
- Abstract: Acteoside was used for anaerobic incubation with rat intestinal flora in vitro. HPLC was used to detect the changes of acteoside at different incubation time points and HPLC-Q-TOF-MS was used to identify the metabolites of acteoside. The results showed that acteoside could be metabolized by rat intestinal flora in vitro and the metabolites were 3,4-dihydroxyphenyl acid, caffeic acid and 3-(3'-hydroxyphenyl) propionic acid.
