Effects of ginkgo diterpene lactones meglumine injection's activated carbon adsorption technology on officinal components.
- Author:
En-li ZHOU
;
Ren-jie WANG
;
Miao LI
;
Wei WANG
;
Dian-hong XU
;
Yang HU
;
Zhen-zhong WANG
;
Yu-an BI
;
Wei XIAO
- Publication Type:Journal Article
- MeSH:
Adsorption;
Charcoal;
chemistry;
Chemistry, Pharmaceutical;
instrumentation;
methods;
Diterpenes;
chemistry;
isolation & purification;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Ginkgo biloba;
chemistry;
Lactones;
chemistry;
isolation & purification
- From:
China Journal of Chinese Materia Medica
2015;40(20):3993-3997
- CountryChina
- Language:Chinese
-
Abstract:
With the diversion rate of ginkgolide A, B, K as comprehensive evaluation indexes, the amount of activated carbon, ad- sorption time, mix rate, and adsorption temperature were selected as factors, orthogonal design which based on the evaluation method of information entropy was used to optimize activated carbon adsorption technology of ginkgo diterpene lactones meglumine injection. Opti- mized adsorption conditions were as follows: adsorbed 30 min with 0.2% activated carbon in 25 °C, 40 r ·min⁻¹, validation test re- sult display. The optimum extraction condition was stable and feasible, it will provide a basis for ginkgo diterpene lactone meglumine injection' activated carbon adsorption process.
