Phenylpropanoids and phenylethanol from flowers of Rosa rugosa.
- Author:
Yue-de WANG
;
Kun ZHOU
;
Wei DONG
;
Gui-you LIU
;
Li-mei LI
;
Jie LOU
;
Qiu-fen HU
;
Yan-qing YE
;
Min ZHOU
- Publication Type:Journal Article
- MeSH:
Cell Line;
Cell Survival;
drug effects;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
pharmacology;
Flowers;
chemistry;
Humans;
Molecular Structure;
Phenylethyl Alcohol;
chemistry;
isolation & purification;
pharmacology;
Rosa;
chemistry;
Spectrometry, Mass, Electrospray Ionization
- From:
China Journal of Chinese Materia Medica
2015;40(20):3998-4001
- CountryChina
- Language:Chinese
-
Abstract:
A new phenylpropanoid (1), together with seven known ones (2-8), has been isolated from the flowers of Rosa rugosa collected from Shanxi province by using various chromatographic techniques. Compound 1 is a new compound, and it displayed cytotoxicity against NB4, SH-SY5Y, PC3, A549 and MCF7 cell lines with IC₅₀ values of 8.2, 6.2, 4.3, 2.8, and 9.6 µmol · L⁻¹ respectively.
