Chemical constituents from whole plants of Valeriana hardwickii.
- Author:
Shi-wei CHAI
;
Yong-song ZHAI
;
Man-yuan WANG
- Publication Type:Journal Article
- MeSH:
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Molecular Structure;
Spectrometry, Mass, Electrospray Ionization;
Valerian;
chemistry
- From:
China Journal of Chinese Materia Medica
2015;40(20):4007-4011
- CountryChina
- Language:Chinese
-
Abstract:
Chemical investigation of the whole plants of Valeriana hardwickii has led to the isolation of 11 flavones and 2 monoterpe- noids by using various chromatographic techniques including column chromatography on silica gel and Sephadex LH-20, preparative TLC, and preparative HPLC. Their structures were identified by spectroscopic data analysis as syzalterin (1), 6-methylapigenin (2), 5-hydroxy-7,4'-dimethoxyflavone (3), genkwanin (4), acacetin (5), apigenin (6), quercetin (7), tricin (8), (-)-farrerol (9), sosakuranetin (10), 5,3',4'-trihydroxy-7-methoxyflavanone (11), (-)-bornyl ferulate ( 12) , and (-)-bornyl caffeate ( 13). All compounds were isolated from this plant for the first time, while compounds 1, 9-13 were obtained from this genus for the first time.
