Induction of apoptosis in colorectal cancer cells by peroxisome proliferators-activated receptor gamma activation up-regulating PTEN and inhibiting PI3K activity.
- Author:
Wei-chang CHEN
1
;
Mao-song LIN
;
Xia BAI
Author Information
1. Department of Gastroenterology, First Affiliated Hospital, Suzhou Univercity, Suzhou 215006, China. weichangchen@126.com
- Publication Type:Journal Article
- MeSH:
Apoptosis;
Cell Line, Tumor;
Colorectal Neoplasms;
drug therapy;
pathology;
HT29 Cells;
Humans;
PPAR gamma;
genetics;
physiology;
PTEN Phosphohydrolase;
Phosphatidylinositol 3-Kinases;
antagonists & inhibitors;
Phosphoric Monoester Hydrolases;
analysis;
Prostaglandin D2;
analogs & derivatives;
pharmacology;
Protein-Serine-Threonine Kinases;
analysis;
Proto-Oncogene Proteins;
analysis;
Proto-Oncogene Proteins c-akt;
Thiazolidinediones;
pharmacology;
Tumor Suppressor Proteins;
analysis;
Up-Regulation
- From:
Chinese Medical Journal
2005;118(17):1477-1481
- CountryChina
- Language:English
