Novel anti-melanoma treatment: focus on immunotherapy.

Author: Meng-Ze HAO ¹ ; Wen-Ya ZHOU ; Xiao-Ling DU ; Ke-Xin CHEN ; Guo-Wen WANG ; Yun YANG ; Ji-Long YANG
Author Information

1. Department of Bone and Soft Tissue Tumor, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Hospital & Institute, Tianjin 30060, P. R. China. yangjilong@tjmuch.com.
Publication Type:Journal Article
MeSH: Humans; Immunotherapy; Melanoma; therapy
From:Chinese Journal of Cancer 2014;33(9):458-465
CountryChina
Language:English
Abstract: Melanoma is an intractable cancer that is aggressive, lethal, and metastatic. The prognosis of advanced melanoma is very poor because it is insensitive to chemotherapy and radiotherapy. The incidence of melanoma has been ascending stably for years worldwide, accompanied by increasing mortality. New approaches to managing this deadly disease are much anticipated to enhance the cure rate and to extend clinical benefits to patients with metastatic melanoma. Due to its high degree of immunogenicity, melanoma could be a good target for immunotherapy, which has been developed for decades and has achieved certain progress. This article provides an overview of immunotherapy for melanoma.