Effects on biomechanical properties of hip articular cartilage degeneration following the femoral neck fracture in rabbits.
- Author:
Wenkai SONG
1
;
Fuxing PEI
;
Ming XIANG
;
Bo LIU
Author Information
1. Department of Orthopedic Surgery, West China Hospital of Sichuan University, Chengdu 610041, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Biomechanical Phenomena;
Cartilage, Articular;
pathology;
physiopathology;
Disease Models, Animal;
Elasticity;
Female;
Femoral Neck Fractures;
pathology;
physiopathology;
Male;
Rabbits;
Stress, Mechanical;
Time Factors
- From:
Journal of Biomedical Engineering
2006;23(5):1024-1027
- CountryChina
- Language:Chinese
-
Abstract:
Osteotomies were performed through post-lateral approach under the base of femoral neck on 60 New Zealand white rabbits. The changes of the thickness and biomechanical properties of acetabular cartilage following the cartilage degeneration and the relationship to the postoperative time 2, 4, 6, 8, 12, 16 weeks later were measured respectively. The cartilage specimens were harvested and measured by the automated creep indentation apparatus to obtain the thickness and biomechanical properties. The cartilage became thicker within 6 weeks after operation, cartilage degeneration developed critically from the surface with the lost of the biomechanical properties. The degeneration progressed till the eartilage became thinner and thinner and the to be torn out into pieces at last. The matrix of articular cartilage degraded markedly for the absence of normal stress load following the femoral neck fracture, led to the decline of the biomechanical properties and kept the degeneration progress to osteoarthritis.
