An association study between the insertion/deletion polymorphism of angiotensin I converting enzyme gene and human speed endurance.
- Author:
Tao LIU
1
;
Xuechuan SUN
Author Information
1. Physical Training & Research Center, PLA Institute of Physical Education, Guangzhou 510502, China. fluentwater3000@21cn.com
- Publication Type:Journal Article
- MeSH:
Adult;
Alleles;
Asian Continental Ancestry Group;
Cluster Analysis;
Exercise Tolerance;
genetics;
Genotype;
Humans;
Lactic Acid;
blood;
Male;
Peptidyl-Dipeptidase A;
genetics;
Polymerase Chain Reaction;
Polymorphism, Genetic
- From:
Journal of Biomedical Engineering
2006;23(5):1045-1047
- CountryChina
- Language:Chinese
-
Abstract:
This study was conducted to research the association between the insertion/deletion (I/D) polymorphism of Angiotensin I converting enzyme (ACE) gene and human speed endurance. Fourty subjects of Han nationality, healthy, with similar sports history were included. The I/D polymorphism of ACE gene was detected by polymerase chain reaction (PCR). The score of 800m run and the concentrations of the whole blood lactic acid were mensurated. Cluster analysis of the grade was made according to the result of cluster analysis. The subjects were divided into two groups: high speed endurance group and low speed endurance group. We found that both the distributions of the ACE genotypes and the distributions of the ACE alleles there were no significant difference between high speed endurance group and low speed endurance group (P > 0.05); Whether at rest state, or after 800m run or the difference value between rest and after 800m run,the concentrations of the whole blood lactic acid did not exist significant difference among three kinds of genotypes groups (P > 0.05). There was on association with I/D polymorphism of ACE gene and human speed endurance.
