Study on the simultaneous quantification of some aminoacids in capsule of astymin fort
- Author:
Lau Van Trinh
- Publication Type:Journal Article
- Keywords:
astymin fort
- MeSH:
Capsules;
acids;
Pharmaceutical Preparations;
drug therapy
- From:Journal of Practical Medicine
2002;435(11):35-38
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A HPLC method on aminoquant 1090 HP-USA was proposed to determine simultaneously 8 Amino acids in Actymin Fort capsules. The chromatographic conditions are: Column is an aminoacid analysis column (HP Part Number 79916AA-572). The mobile phase for channel A is a 20 mM sodium acetate buffer containing 0.1018% (v/v) Triethylamine (TEA), adjusted to pH 7.2 with 1-2% Acetic acid, and with 0.3% Tetrahydrofuran (THF).100 mM sodium acetate buffer, adjusted to pH 7.2 with 1-2% acetic acid, 40 p. pf Acetonitrile and 40 p. of methanol. Flow rate is 0.45ml/min. The diode array detector was used. It was detected at wavelength of 338 nm and reference wavelength of 390 nm. The experimental results showed that the proposed method is accurate and precise.
