Observation on clinical effect of Angelica injection in treating acute cerebral infarction.
- Author:
Yu-min LIU
1
;
Jun-jian ZHANG
;
Jian JIANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Aged; Aged, 80 and over; Angelica sinensis; chemistry; Cerebral Infarction; drug therapy; Drugs, Chinese Herbal; administration & dosage; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Phytotherapy
- From: Chinese Journal of Integrated Traditional and Western Medicine 2004;24(3):205-208
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the therapeutic effect of Angelica Injection (AI) in treating acute cerebral infarction (ACI).
METHODSOne thousand four hundred and four patients, who were treated with AI (692 patients in Group A), compound salvia (390 patients in Group B) and low molecular dextran injection (322 patients in Group C) respectively. Indexes such as CT scanning on infarcted volume, scoring of clinical neuro-function deficit taking on the 1st, 3rd, 7th, 15th and 25th day, clinical therapeutic effectiveness evaluated by the end of the 2nd week and the improvement of Barthel index scores were observed.
RESULTSThe total effective rate in Group A, B and C was 78.7%, 63.6% and 59.3% respectively, that in Group A was significantly higher than in the other two groups (P < 0.05). The improvement of neuro-function deficit scores and Barthel scores in Group A were better than those in Group B and C (on the 25th day, P < 0.01), and the decrement of infarcted volume in Group A was larger than that in Group C (P < 0.01).
CONCLUSIONAI has evident therapeutic effect in treating ACI.
