Clinical observation on effect of xuesaitong injection as auxiliary treatment of severe craniocerebral injury.
- Author:
Wen-bing AI
1
;
Yu-hong CHEN
;
Qi-jian YANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adult; Brain Injuries; drug therapy; surgery; Craniocerebral Trauma; drug therapy; surgery; Drug Therapy, Combination; Drugs, Chinese Herbal; therapeutic use; Female; Glasgow Coma Scale; Glasgow Outcome Scale; Humans; Male; Neuroprotective Agents; therapeutic use; Panax; chemistry; Phytotherapy; Saponins; administration & dosage
- From: Chinese Journal of Integrated Traditional and Western Medicine 2004;24(3):213-215
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of Xuesaitong injection (XSTI, a preparation of Panax Notoginseng) as auxilliary treatment of severe craniocerebral injury.
METHODSEighty-seven patients with severe craniocerebral injury were selected and randomly divided into the treated group (n = 44) and the control group (n = 43), they were treated with conventional treatment, and XSTI was given additionally to the treated group. Intracranial pressure (ICP) and Glasgow coma score (GCS) of all patients were measured after 1 or 2-week treatment, and Glasgow outcome scale (GOS) of them was determined 3 months later. Then the therapeutic effect in the two groups were compared.
RESULTSAfter treatment, the ICP was lower, GCS higher and GOS better in the treated group than those in the control group significantly, all showing statistical significance (P < 0.05).
CONCLUSIONXSTI has marked clinical therapeutic effect in treating patients with severe craniocerebral injury.
