Role of immunologic abnormality in recurrent parotitis in children.
- Author:
Wen-hua YUAN
1
;
Ji-mei SU
;
Xiao-wei YE
;
Xiao-jia HUANG
;
Zhi-fang WU
Author Information
- Publication Type:Journal Article
- MeSH: CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; cytology; immunology; Child; Child, Preschool; Female; Humans; Immunoglobulin A; blood; Immunoglobulin E; blood; Immunoglobulin G; blood; Infant; Male; Parotitis; immunology; Recurrence
- From: Journal of Zhejiang University. Medical sciences 2010;39(4):419-423
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the relationship between immune function and the recurrent parotitis (RP) for children.
METHODSThe children diagnosed as RP were divided into two groups: aged under 6y and over 6y and the immune function were measured and compared with that of normal children.
RESULTSFor RP children the ratio of CD4+ T cell in over 6y group was significantly lower than that in under 6y group (P<0.05), while IgG value in over 6y group was higher than that in under 6y group (P<0.05). Compared with normal children, RP children in under 6y group had higher CD8+ T cell ratio and IgG, IgE, IgA and C3 value (P<0.01) and lower CD4+ T cell ratio (P<0.01), while RP children over 6y group, they had higher CD8+ T cell ratio, IgE value (P<0.01) and C3 (P<0.05), lower CD4
CONCLUSIONImpaired immune function may play an important role in the recurrent parotitis in children.
