Research progress on expression and function of Toll-like receptors in dendritic cells.
- Author:
Jia GUO
1
;
Jian-ping PAN
Author Information
1. Department of Microbiology and Parasitology, College of Medicine, Zhejiang University, Hangzhou 310058, China.
- Publication Type:Journal Article
- MeSH:
Dendritic Cells;
immunology;
metabolism;
Humans;
Immunity, Innate;
Signal Transduction;
Toll-Like Receptors;
metabolism;
physiology
- From:
Journal of Zhejiang University. Medical sciences
2010;39(4):436-441
- CountryChina
- Language:Chinese
-
Abstract:
Dendritic cells (DCs), the most potent antigen-presenting cells, recognize pathogen by Toll-like receptors (TLRs) and serve as the bridge between the innate and the adaptive immune responses. TLRs-mediated signal transduction plays a crucial role in the functional maturation of DCs. This review summarizes the research progress on the expression and function of TLRs in DCs.
