Advance in studies on anti-infection of andrographolide and its derivatives in past 10 years.
- Author:
Yuan-Yuan YAN
1
;
Gao-Xiang SHI
2
;
Jing SHAO
2
;
Tian-Ming WANG
2
;
Chang-Zhong WANG
2
Author Information
1. School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China. 1136510704@qq.com
2. School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China.
- Publication Type:Journal Article
- MeSH:
Andrographis;
chemistry;
Animals;
Anti-Infective Agents;
chemistry;
pharmacology;
Diterpenes;
chemistry;
pharmacology;
Drugs, Chinese Herbal;
chemistry;
pharmacology;
Humans;
Structure-Activity Relationship
- From:
China Journal of Chinese Materia Medica
2013;38(22):3819-3824
- CountryChina
- Language:Chinese
-
Abstract:
Andrographolide (AG) is a main effective ingredient in leaves of Andrographis paniculata. AG and its derivatives have such effects in anti-infection, anti-tumor and immuno-regulation. Particularly, its antibacterial, antiviral and anti-protozoal activities play an increasingly important role in resisting opportunistic infections. On the basis of our studies on AG over the years, we made a summary for the basis and clinical studies on AG and its derivatives over the past 10 years.
