Prognostic Factors Associated with Poor Outcome of Biofeedback Therapy for Constipated Patients with Pelvic Outlet Obstruction.
10.3393/jksc.2008.24.5.313
- Author:
Sung Jin KIM
1
;
Yong Hee HWANG
;
Yong Hwan JUNG
Author Information
1. Department of Surgery, Seoul Adventist Hospital, Seoul, Korea. hwangyon@hotmail.com
- Publication Type:Original Article
- Keywords:
Pelvic outlet obstruction;
Biofeedback;
Constipation
- MeSH:
Biofeedback, Psychology;
Constipation;
Defecation;
Defecography;
Demography;
Electromyography;
Follow-Up Studies;
Humans;
Manometry
- From:Journal of the Korean Society of Coloproctology
2008;24(5):313-321
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The aim of this study was to identify the prognostic factors associated with poor outcome of biofeedback therapy. METHODS: One hundred thirty-seven (137) constipated patients with pelvic outlet obstruction (median age 49 years) had more than one biofeedback session after defecography. Follow-up data (mean follow-up: 14 months; range: 2~37 months) were obtained in 114 patients. Any differences in demographics, clinical symptoms, and parameters of an anorectal physiological study were evaluated between the success group and the failure group. RESULTS: At follow-up, 80 (70 percent) patients felt improvement in symptoms, but 34 (30 percent) patients did not. Pre-biofeedback presence of symptoms of difficult defecation predict poor outcome (88 vs. 69 percent for failure vs. success, P<0.05). The positive and the negative predictive values of difficult defecation for poor outcome were 35 percent and 86 percent, respectively. A negative mean pressure change on pre-biofeedback anal manometry was related to a poor outcome (65 vs. 26 percent for failure vs. success, P<0.001). The positive and the negative predictive values of negative mean pressure change for poor outcome were 51 percent and 83 percent, respectively. A negative electrical current change on pre-biofeedback anal electromyography was related to a poor outcome (23 vs. 9 percent for failure vs. success, P<0.05). The positive and the negative predictive values of negative electrical-current change for poor outcome were 53 percent and 74 percent, respectively. CONCLUSIONS: Difficult defecation, negative mean pressure change in pre-biofeedback anal manometry, and negative electrical current change in pre-biofeedback anal electromyography were predictors associated with poor outcome of biofeedback therapy for constipated patients with pelvic outlet obstruction.