Evaluation of pulmonary microvascular permeability in isolated perfused rabbit lungs.
- Author:
Hua XIN
1
;
Ya-Juan ZHENG
;
Ji-Dong YAN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Capillary Permeability; In Vitro Techniques; Lung; blood supply; Male; Perfusion; Pulmonary Circulation; Rabbits
- From: Chinese Journal of Applied Physiology 2002;18(2):201-203
- CountryChina
- Language:Chinese
-
Abstract:
AIMTo quantity and accurately evaluate pulmonary microvascular permeability.
METHODSTo measure capillary fluid filtration coefficient (Kf) by using the gravimetric method in isolated perfused rabbit lungs.
RESULTSThe amount of Kf is 4.78 +/- 0.73 mg x min(-1) x cmH2O(-1) x g(-1).
CONCLUSIONThe advantage of this method is exactly and directly. This method shows the important effect on realizing the pulmonary physiologic condition and evaluating the extent of acute lung edema and injury.