Genetic risks of intracytoplasmic sperm injection for male infertility.
- Author:
Fa-Ming SHAO
1
;
Xiao-Bin ZHU
;
Zheng LI
Author Information
1. Department of Urology, Affiliated Hospital of Ningbo University School of Medicine, Ningbo, Zhejiang 315020, China. ybchenjian@126.com
- Publication Type:Journal Article
- MeSH:
Chromosomes, Human, Y;
genetics;
Genetic Loci;
Humans;
Infertility, Male;
genetics;
therapy;
Male;
Seminal Plasma Proteins;
genetics;
Sperm Injections, Intracytoplasmic
- From:
National Journal of Andrology
2008;14(1):71-74
- CountryChina
- Language:Chinese
-
Abstract:
Recently, intracytoplasmic sperm injection (ICSI) has been extremely successful in the treatment of male infertility. However, the consequent transmission of sperm cytogenetic defects and genetic defects to the offspring has aroused considerable concern. Among infertile men, those with severe spermatogenic defects, including oligozoospermia and azoospermia, are mostly the subjects for ICSI. Therefore it is very important to obtain cytogenetic and chromosomal information on these infertile patients and prevent the inheritance of these genetic defects. This review offers an analysis on the genetic defects among infertile men.
