Updated application of prostate-specific membrane antigen to the diagnosis and treatment of prostate cancer.
- Author:
Qing-Lai TANG
1
;
Mao-Yin YAO
Author Information
1. Department of Urology, Zhongda Hospital, Southeast University, Nanjing, Jiangsu 210009, China. qinglaitang@hotmail.com
- Publication Type:Journal Article
- MeSH:
Antigens, Surface;
genetics;
Gene Expression Regulation, Neoplastic;
Glutamate Carboxypeptidase II;
genetics;
Humans;
Male;
Prostate-Specific Antigen;
genetics;
Prostatic Neoplasms;
diagnosis;
genetics;
therapy;
RNA, Messenger;
genetics;
metabolism;
Reverse Transcriptase Polymerase Chain Reaction
- From:
National Journal of Andrology
2008;14(1):79-82
- CountryChina
- Language:Chinese
-
Abstract:
Prostate-specific membrane antigen (PSMA), the research of which has flourished in recent years, is a specific prostate cancer marker. PSMA plays a more and more important role in the early diagnosis, gene treatment and prognosis of the disease course of prostate cancer. This review focuses on the progress in researches of the structure, function, expression traits and gene expression of the PSMA protein, prostate cancer radioimmunoimaging, DNA vaccines and suicide gene therapy based on PSMA, as well as the role of PSMA in the clinical diagnosis and treatment of prostate cancer.
