Relationship between RhoA/Rho-kinase signaling pathway and penile erection.
- Author:
Ping-Yu ZHU
1
;
Rui JIANG
Author Information
1. Department of Urology, the Affiliated Hospital of Luzhou Medical College, Luzhou, Sichuan 646000, China. zhupy1999_2004@sohu.com
- Publication Type:Journal Article
- MeSH:
Animals;
Humans;
Male;
Penile Erection;
physiology;
Rabbits;
Signal Transduction;
physiology;
rho-Associated Kinases;
metabolism;
rhoA GTP-Binding Protein;
metabolism
- From:
National Journal of Andrology
2008;14(2):155-158
- CountryChina
- Language:Chinese
-
Abstract:
Erectile dysfunction (ED) has been plaguing men for a long time and the incidence of this disease is as high as 52% among males aged between 40 and 70. Recent discovery has shown a connection between the RhoA/Rho-kinase signaling system and ED. This paper reviews the progress in the study of RhoA/Rho-kinase signaling pathway, expounds its mechanism in penile erection and provides a base for further research on the role of RhoA/Rho-kinase signaling pathway in penile erection.
