Impregnate occasion for male renal transplant recipients.
- Author:
Long-Gen XU
1
;
Xiao-Feng ZHU
;
Li-Ming JIN
;
Hui-Ming XU
;
Xia LING
;
Xiao-Yang TANG
;
Biao XU
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Coitus; Cyclosporine; administration & dosage; therapeutic use; Dose-Response Relationship, Drug; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents; administration & dosage; therapeutic use; Kidney Transplantation; Male; Postoperative Period; Semen; chemistry; cytology; drug effects; Sperm Count; Sperm Motility; drug effects; Time Factors
- From: National Journal of Andrology 2008;14(5):448-450
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the impregnate occasion for male renal transplant recipients.
METHODSTwenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at the dose of 4.1-6 mg/[kg x d]), 11 in Group B (6-24 months and 2.1-4 mg/[kg x d]) and 8 in Group C (longer than 24 months and 1.3-2 mg/[kg x d]). The semen of the patients were detected and compared with those of 12 normal volunteers.
RESULTSStatistically significant differences were observed in sperm motility and sperm head deformity between Group A and C (P < 0.05), but not in pH value and sperm volume, vitality and concentration among the 3 groups (P > 0.05).
CONCLUSIONFor male renal transplant recipients, 2 years or longer after the transplantation is the most suitable time for impregnation.