Atypical Cogan's syndrome associated with coronary disease.
- Author:
Ivanovic BRANISLAVA
1
;
Tadic MARIJANA
;
Damjanov NEMANJA
;
Simic DRAGAN
;
Zlatanovic MAJA
Author Information
1. Clinic for Cardiology, Clinical Centre of Serbia, Belgrade 11000, Serbia. lole@scnet.rs
- Publication Type:Case Reports
- MeSH:
Adult;
Cogan Syndrome;
complications;
Coronary Disease;
etiology;
Female;
Humans
- From:
Chinese Medical Journal
2011;124(19):3192-3194
- CountryChina
- Language:English
-
Abstract:
Cogan’s syndrome (CS) is a rare inflammatory disorder characterized by interstitial keratitis and vestibuloauditory abnormalities often associated with various systemic manifestations. Involvement of cardiovascular system resembling systemic vasculitis may lead to severe complications and death. The present report describes a case of a female patient with atypical Cogan's syndrome presented with systemic manifestations and severe coronary and femoral artery stenosis. Despite the clinical improvement after glucocorticoids and cyclophosphamide, the patient required double aortocoronal bypass grafting one year letter. During three years follow-up, she was in stable condition, without stenocardial symptoms and claudication and her inflammatory parameters remain normal. This case highlights the rare involvement of coronary arteries without associated large-vessel vasculitis of the aortic arch in CS.
