Expression of testosterone in the rapid growing rat condylar cartilage and the expression changes after the function mandibular advancement.
- Author:
Xiao-bin LI
1
;
Kai-yun CHEN
;
Zheng ZHOU
;
Song-jiao LUO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Cartilage; growth & development; metabolism; Male; Mandibular Advancement; Mandibular Condyle; growth & development; metabolism; Orthodontic Appliances, Functional; Random Allocation; Rats; Rats, Sprague-Dawley; Testosterone; metabolism
- From: West China Journal of Stomatology 2004;22(1):29-31
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the expressions of Testosterone in the condylar cartilage of rapid growing rats.
METHODSThe mimic functional appliances were used in experiment groups and rats were killed after 3 days, 1 week, 2 weeks, 3 weeks and 4 weeks. Immunohistochemical technique was used to detect the expression of T.
RESULTST was expressed throughout the condylar cartilage. The Highest expressions were in mature layers of both experiment and control groups. Along with the maturation, the expressions of T in the condylar cartilage were changed respectively, and the immunostain levels in the mature layer of experiment groups 2 and 3 weeks were higher than those of control groups (P < 0.05).
CONCLUSION1. T is a member of cartilage growth and development control system. 2. The orthopedic mechanism of functional appliance may be conducted by T.
