Effect of para-aminobenzonic acid (PABA) on cell-surface hydrophobicity of Streptococcus mutans.

Author: Yan-hong LI ¹ ; Xue-dong ZHOU ; Xiao-rong XIAO ; Ji-yao LI ; Qian LIU ; Gang LI
Author Information

1. Dept. of Preventive Dentistry, First Affiliated Hospital, Kunming Medical University, Kunming 650031, China.
Publication Type:Journal Article
MeSH: 4-Aminobenzoic Acid; pharmacology; Bacterial Adhesion; drug effects; Humans; Hydrophobic and Hydrophilic Interactions; Streptococcus mutans; drug effects; physiology
From: West China Journal of Stomatology 2004;22(2):149-151
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the effect of Para-aminobenzonic acid on cell-surface hydrophobicity of Streptococcus mutans.
METHODSMicrobial adhesion to hydrocarbons (MATH) was used to measure the cell-surface hydrophobicity of Streptococcus mutans which grew in modified Carlsson medium with different dilutions of PABA.
RESULTSThe cell-surface hydrophobicity of Streptococcus mutans increased when Carlsson medium contained low dilution of PABA. But following the increase of PABA, the cell-surface hydrophobicity decreased.
CONCLUSIONPara-aminobenzonic acid could inhibit the adherence of Streptococcus mutans through changing its cell-surface hydrophobicity.