Expression of proliferating cell nuclear antigen/bcl-2 in gray gingival tissue.
- Author:
Lin CHEN
1
;
Guo-wei ZHU
;
Xiao-hong YANG
;
Hua-qing LIU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Crowns; Gingiva; metabolism; pathology; Metal Ceramic Alloys; Proliferating Cell Nuclear Antigen; biosynthesis; Proto-Oncogene Proteins c-bcl-2; biosynthesis; Rabbits
- From: West China Journal of Stomatology 2004;22(3):180-182
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the expression of PCNA/bcl-2 protein in gray and normal gingival tissue, and to investigate the biological effect of procelain-fused-to-metals (PFM).
METHODSGray gingival tissue animal model was established by PFM prosthesis and immunohistochemistry S-P method was used to detect the PCNA/bcl-2 protein expression in gingival tissue after 3 months, 6 months in PFM groups and control group.
RESULTSThe expression of PCNA had significant difference between the 3th month group and the control group (P < 0.05); no significant difference was found between the 6th month group and the control group (P > 0.05). The expression of bcl-2 had no significant difference between the 6th month group and the control group (P > 0.05).
CONCLUSIONThere were a correlation between the expression of PCNA and inflammation of the gray gingival tissue; The expression of PCNA and bcl-2 protein does not indicate that gray gingival tissue had dysplasia change.
