Attenuation of chronic stress-induced hippocampal damages following physical exercise.
- Author:
Qiang MA
1
;
Jing WANG
;
Hong-Tao LIU
;
Fu-Huan CHAO
Author Information
1. Institute of Health and Environmental Medicine, Academy of Military Medical Sciences, Tianjin, China. maqiangw@Hotmail.com
- Publication Type:Journal Article
- MeSH:
Animals;
Corticosterone;
blood;
Hippocampus;
physiopathology;
Long-Term Potentiation;
Male;
Motor Activity;
Rats;
Rats, Wistar;
Restraint, Physical;
Stress, Psychological;
blood;
physiopathology
- From:
Acta Physiologica Sinica
2002;54(5):427-430
- CountryChina
- Language:Chinese
-
Abstract:
The long-term potentiation (LTP) in the hippocampal dentate gyrus and the plasma glucocorticoids level were observed in rats to study the effects of physical exercise on chronic stress-induced hippocampal damages. Eight-week spontaneous wheel running exercise could attenuate the suppression of LTP induced by 21-day restraint stress, and maintain the normal plasma glucocorticoids levels. It is suggested that long-term physical exercise may protect the hippocampus from stress-induced damages.
