Meta-analysis on the relationship of chlamydia pneumonia infection and coronary heart disease.
- Author:
Shu-kang WANG
1
;
Jie-zhen WANG
Author Information
- Publication Type:Journal Article
- MeSH: Antibodies, Bacterial; blood; Chlamydia Infections; Chlamydophila pneumoniae; Coronary Disease; microbiology; Enzyme-Linked Immunosorbent Assay; Humans; Risk Factors
- From: Acta Academiae Medicinae Sinicae 2005;27(3):349-353
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo determine the relationship of chlamydia pneumonia (CP) infection and coronary heart disease (CHD).
METHODSStudies published before 2004 that had reported on correlations between CHD and CP were collected. Studies were sorted into four sorts according to different testing methods. We determined to use either fixed effect model or random effect model according to the result of heterogeneity test. Meta-analysis was done by RevMan 4.2.
RESULTSTotally 29 studies were included into the review. The odd ratio (OR) to review all literature enzyme-linked immunosorbent assay (ELISA), dot-immunogdd filtration assay (DIGFA), and micro-immunofluorescence (MIF) was 4.00 (3.07, 5.22), 2.86 (1.89, 4.32), 14.89 (1.46, 151.57), and 4.46 (3.15, 6.32).
CONCLUSIONCP infection is associated with CHD, CP infection may be one of the risk factors of CHD.
