Expression of galectin-3 in invasive prolactinomas.
- Author:
Hong WANG
1
;
Ming-dong WANG
;
Wen-bin MA
;
Di YANG
;
Yan-Fang SHI
;
Yan-guo KONG
;
Shi-fang LI
;
Zhi-hong LI
;
Ren-zhi WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Female; Galectin 3; biosynthesis; genetics; Humans; Male; Middle Aged; Neoplasm Invasiveness; Pituitary Neoplasms; metabolism; pathology; Prognosis; Prolactinoma; metabolism; pathology
- From: Acta Academiae Medicinae Sinicae 2005;27(3):380-381
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the expression of galectin-3 (Gal-3) in prolactinomas.
METHODSExpressions of Gal-3 were evaluated by immunohistochemistry using polyclonal antibody in 16 invasive prolactinomas and 16 prolactinomas.
RESULTSGal-3 was expressed both in invasive prolactinomas and noninvasive prolactinomas while significantly higher expression seen in the invasive prolactinomas (P < 0.05).
CONCLUSIONGal-3 expression may be used as a useful indicator to determine the invasiveness and prognosis of prolactinomas.
