Research status of genodermatoses in China.
- Author:
Xue-Jun ZHANG
1
;
Jian-jun CHEN
;
Min GAO
Author Information
1. Key Laboratory of Genome Research at Anhui, Institute of Dermatology, Anhui Medical University, Hefei 230032, China. ayzxj@vip.sina.com.cn
- Publication Type:Journal Article
- MeSH:
Erythromelalgia;
genetics;
HLA Antigens;
genetics;
Humans;
NAV1.7 Voltage-Gated Sodium Channel;
Proteins;
genetics;
Psoriasis;
genetics;
Sodium Channels;
genetics;
Vitiligo;
genetics
- From:
Acta Academiae Medicinae Sinicae
2005;27(3):408-414
- CountryChina
- Language:Chinese
-
Abstract:
Among over 300 genodernatoses, causative genes have been identified in 170 monogenetic diseases, while gene mapping has been performed in over 100 monogenetic and polygenctic skin diseases. Researches in genodermatoses has rapidly advanced in China in recent ten years. The causative genes involved in multiple familial trichoepithelioma and primary erythermalgia have been found. Two independent genome-wide scans with DNA markers have been performed to detect genetic linkage related to psoriasis and vitiligo. In this review article, we summarize these most recent findings.
