A vasoactive peptide: urotensin II.
- Author:
Guo-Qiang LIU
1
;
Zheng-Pei ZENG
Author Information
1. Department of Endocrinology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Arteriosclerosis;
etiology;
Humans;
Hypertension;
etiology;
Receptors, G-Protein-Coupled;
chemistry;
metabolism;
physiology;
Urotensins;
chemistry;
metabolism;
physiology;
Vasoconstrictor Agents;
chemistry;
metabolism;
pharmacology
- From:
Acta Academiae Medicinae Sinicae
2005;27(4):525-528
- CountryChina
- Language:Chinese
-
Abstract:
Urotensin II (U II ) is currently the most potent vasoconstrictor. G-protein coupled receptor 14 ( GPR-14) is its specific receptor. This review mainly discribes the structure and distribution of U II and GPR14, the activities that U II and GPR14 stimulates proliferation of vascular smooth muscle cells and vasoconstriction, as well as its mechanism.
