Clinical comparison on the classical versus extensive Whipple's resection for adenocarcinoma of head of pancreas.
- Author:
Xu-bao LIU
1
;
Lü-nan YAN
;
Hong-jun ZHAI
;
Bing LU
;
Wei-ming HU
;
Bo-le TIAN
;
Zhao-da ZHANG
Author Information
- Publication Type:Clinical Trial
- MeSH: Adenocarcinoma; mortality; surgery; Adult; Aged; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms; mortality; surgery; Pancreaticoduodenectomy; methods; Postoperative Complications; epidemiology; Retrospective Studies; Survival Rate
- From: Acta Academiae Medicinae Sinicae 2005;27(5):575-578
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of extensive Whipple's resection to the adenocarcinoma of head of pancreas on the survival, complications, and surgical mortality.
METHODNinety three patients who received Whipple's surgery between January 1995 and March 2003 were divided into classical group (n = 51) and extensive group (n = 42). Their short-term outcome and survival rate were compared retrospectively.
RESULTSThe postoperative complication rate and mortality in classical group and extensive group were 19.61%/3.92% and 16.67%/2.38%, respectively. And 1- and 2- year survival rates in classical group and extensive group were 58.82%/20.59% and 63.33%/23.33%, respectively.
CONCLUSIONSPostoperative complications and mortality will not increase in extensive Whipple's resection for adenocarcinoma of head of pancreas. However, whether extensive Whipple's resection will improve long-term survival still requires further investigation.