Effects of ouabain at low concentrations on growth of leukemia cells.
- Author:
Min WANG
1
;
Run-Ming JIN
;
Yi-Ning QIU
;
Wen LIN
;
Bing MENG
Author Information
1. Department of Pediatrics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.
- Publication Type:Journal Article
- MeSH:
Cell Line, Tumor;
Cell Proliferation;
drug effects;
Dose-Response Relationship, Drug;
Humans;
Leukemia;
pathology;
Leukemia, Megakaryoblastic, Acute;
pathology;
Ouabain;
pharmacology;
Sodium-Potassium-Exchanging ATPase;
metabolism
- From:
Journal of Experimental Hematology
2007;15(6):1165-1168
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed to investigate the effects of ouabain at low concentrations on growth regulation in various leukemia cell lines and to determine the therapeutic potential of ouabain in leukemia. By using MTT, flow cytometry (FCM), the changes in cell growth and cell cycle of leukemia cell lines were observed after treating with ouabain at low concentrations (
