Quality control of indispensable reagent RBC for ABO typing.
- Author:
Shu-Hong LIU
1
;
Hua XU
;
Hai-Tao WU
;
Yong-Qi ZHAO
;
Ming FAN
Author Information
1. Institute of Basic Medical Sciences, Academy of Military Medical Sciences, Beijing 100850, China.
- Publication Type:Journal Article
- MeSH:
ABO Blood-Group System;
Blood Grouping and Crossmatching;
standards;
Erythrocytes;
immunology;
Humans;
Indicators and Reagents;
Quality Control
- From:
Journal of Experimental Hematology
2007;15(6):1289-1292
- CountryChina
- Language:Chinese
-
Abstract:
The reagent RBC of known blood group is indispensable reagent for detecting antibody in serological identification of ABO blood group. To elevate the accuracy of detection and solve problems for standardization and quality control of prepared reagent RBC, the detection of specificity and affinity of reagent RBC, shaking test, flow cytometry and atomic force microscopy were performed. On the basis of screening and establishing the reagent for quality control, methods for quality inspection and quality control were established. The results indicated that the prepared reagent RBC evaluated in three batches ensured the quality and performance, and decreased the variance between different batches of the products to the utmost. In conclusion, the quality control problems of prepared reagent RBC had been solved and the accuracy of detection for blood types also elevated.
