Pharmaceutical study on multi-component traditional Chinese medicines.
- Author:
Yi FENG
1
;
Xiao LIN
;
Lan SHEN
;
Yan-Long HONG
Author Information
1. Engineering Research Center of Modern Traditional Chinese Medicine Preparation Technology of Ministry of Education, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. fyi@vip.sina.com
- Publication Type:Journal Article
- MeSH:
Chemical Phenomena;
Drug Compounding;
Drug Dosage Calculations;
Medicine, Chinese Traditional;
methods;
Models, Theoretical
- From:
China Journal of Chinese Materia Medica
2013;38(5):629-632
- CountryChina
- Language:Chinese
-
Abstract:
Due to the limitation of science and technology in ancient times, traditional Chinese medicines (TCMs) could have prepared only in traditional dosage forms, such as pills, powders, ointments and pellets. Though studies on multi-component TCMs have become one of major development orientations of TCM, the druggability of their preparations has always been neglected. On the basis of two key difficulties--the integration of studies on multi-component TCMs and TCM theory as well as the evaluation on their druggability, the essay proposes methods and technologies that can be adopted in studies on multi-component TCM preparations, including the characteristic physicochemical property of multi-component TCMs and its correlation with forming process, the release-modified micro pill preparation technology based on prescription-symptom-dosage, and the evaluation technology on release of release-modified micro pill components based on mathematical set model.