Analysis on genotype distributions and epidemiological characteristics of Yersinia pestis plague foci in Gansu province.
- Author:
Xin-hua WANG
1
;
Hong ZHANG
;
Li-min GUO
;
Ke-jun MIAO
;
Wen-ping DA
;
Bin WU
;
Da-qin XU
;
Ya-jun GE
;
Tao-xia MU
;
Guo-juan CHEN
;
Xiao-yan ZHOU
;
Shi-ming WANG
;
Peng-fei GE
;
Jin-xiao XI
Author Information
- Publication Type:Journal Article
- MeSH: Animals; China; epidemiology; DNA Primers; Genetic Variation; Genome, Bacterial; Genotype; Humans; Plague; epidemiology; microbiology; Yersinia pestis; genetics; isolation & purification
- From:Chinese Journal of Epidemiology 2013;34(5):433-437
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the genotype distributions and epidemiological characteristics of Yersinia pestis in Gansu province.
METHODSPrimers were designed according to the confirmed 23 differential sections, to genotype the 202 Yersinia pestis DNA of Gansu province by PCR, and to analyze its distribution and epidemiological characteristics.
RESULTSYersinia pestis in Gansu province could be divided into eight genotypes: 1b, 5, 7, 8, 13, 26, new genotype 1 (GS1) and new genotype 2 (GS2). They were distributed in various regions. 1b, 8 and GS1 genotypes of Yersinia pestis had been identified since 1960s but the 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had been isolated since 1990s.
CONCLUSION1b, 8 and GS1 genotypes of Yersinia pestis continued to be violently prevalent since 1960s but 7, 13 and 26 genotypes had not been isolated for more than 40 years while GS2 and 5 genotypes had started to be popular since 1990s.
