MRI features of olfactory bulb volume in healthy middle and old-aged persons
10.3760/cma.j.issn.1673-0860.2009.12.010
- VernacularTitle:磁共振成像测量健康中老年人嗅球体积的特点
- Author:
Jian WANG
1
;
Hui YOU
;
Zhen-Xin ZHANG
;
Jing GUAN
;
Xing-Ming CHEN
;
Jian-Feng LIU
;
Da-Hai YANG
;
Ying-Ying SHANG
;
Ying-Ying ZHU
;
Qi-Juan ZOU
;
Zhi-Qiang GAO
;
Dao-Feng NI
Author Information
1. 中国医学科学院中国协和医科大学北京协和医院
- Keywords:
Olfactory bulb;
Age groups;
Sex factors;
Magnetic resonance imaging
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2009;44(12):1006-1009
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differences of olfactory bulb(OB)volumes between younger and older,male and female,left-side and right-side in healthy middle and old-aged persons by MRI.Methods Ninety five healthy middle and old-aged volunteers(male:female=45:50)were divided into 2 groups,group one included persons aged from 50 to 69,group two included persons elder than 70.The left-side,right-side and both-side volumes of OB,the volumes of brain and the ratio of OB/brain were measured by MRI.Results(1)The left-side and both-side volumes of OB(x-±s),the volumes of brain [(39.89 ±8.7)mm~3,(81.70 ± 16.8)mm~3 and(1281.86 ± 140.2)cm~3]in 50-69 years old group were respectively larger than those in ≥70 years old group[(34.45 ± 10.4)mm~3,(72.10 ± 19.3)mm~3 and (1165.77 ± 165.3)cm~3],and the differences reached statistical significance(t were respectively 2.649,2.449,3.516,all P＜0.05).There were no significant differences of right-side OB volumes and the ratio of OB/brain between 50-69 years old group and ≥70 years old group(t were respectively 1.904,0.616,each P＞0.05).(2)The male's OB volumes of left-side,right-side and both-side,the brain volumes and the ratio of OB/brain were respectively larger than females',and the differences reached statistical significance(t were respectively 4.461,3.630,4.399,3.800,2.400,all P＜0.05).(3)The right-side OB volumes were larger than left-side's and significant differences were found in female group,50-60 years old group and ≥70 years old group(t were respectively 2.732,2.117,3.516,all P＜0.05).There were no significant differences of OB volumes between left-side and right-side in female(t=2.649,P=0.110).The ratio of right-side OB/brain were larger than the ratio of left-side's and the differences reached statistical significance(t=3.183,P=0.002).Conclusions MRI could be used to measure the volume of OB.The older the people,the smaller the OB volumes.There was no influence of age on the ratio OB/brain.The OB volumes of right-side were larger than those of left-side.The OB volumes of male were larger than those of female.
