A Case of Polymyositis Associated with Immunoglobulin A Nephropathy.
10.4078/jrd.2017.24.4.241
- Author:
Yoon Jeong OH
1
;
Eun Sung PARK
;
Mi JANG
;
Ea Wha KANG
;
Jeong Hae KIE
;
Sang Won LEE
;
Jason Jungsik SONG
;
Yong Beom PARK
;
Chan Hee LEE
;
Jin Su PARK
Author Information
1. Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Polymyositis;
IgA nephropathy;
Proteinuria
- MeSH:
Biopsy;
Creatinine;
Edema;
Female;
Gastrointestinal Tract;
Glomerulonephritis;
Glomerulonephritis, IGA*;
Humans;
Hypoalbuminemia;
Immunoglobulin A*;
Immunoglobulins*;
Middle Aged;
Muscles;
Myalgia;
Myositis;
Phosphotransferases;
Polymyositis*;
Proteinuria;
Weight Gain
- From:Journal of Rheumatic Diseases
2017;24(4):241-245
- CountryRepublic of Korea
- Language:English
-
Abstract:
Polymyositis (PM) is a chronic inflammatory disease that predominantly affects muscles. Systemic organ involvement, including the respiratory and gastrointestinal tracts, is frequently observed in PM, but renal involvement is rare. Herein, we report the case of a 56-year-old woman presenting with weight gain, edema, and generalized myalgia. Laboratory tests revealed elevated creatinine kinase level, hypoalbuminemia, and proteinuria. Histopathological examination of muscle biopsy revealed inflammatory myositis, and a renal biopsy confirmed immunoglobulin A (IgA) nephropathy. Based on the clinico-pathological results, the patient was diagnosed with PM with IgA nephropathy. This is a report of a rare occurrence of IgA nephropathy in a patient with PM presenting with chronic glomerulonephritis.