Rapid eye movement-related and none rapid eye movement-related classification in obstructive sleep apnea hypopnea syndrome
10.3760/cma.j.issn.1673-0860.2010.02.004
- VernacularTitle:阻塞性睡眠呼吸暂停低通气综合征快动眼与非快动眼分型的多道睡眠图分析
- Author:
Li-Ping CHAI
1
;
Xuan XIE
;
Yu-Hui ZENG
;
Zhang-Feng WANG
;
Xiu-Ping TU
Author Information
1. 中山大学附属第一医院(耳鼻咽喉科医院)
- Keywords:
Sleep,REM;
Polysomnography;
Sleep apnea,obstructive
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2010;45(2):105-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the value of a new measurement that divided obstructive sleep apnea-hypopnea syndrome (OSAHS) into rapid-eye-movement (REM) related and non-rapid-eye-movement (NREM) related subgroups.Methods According to Siddiqui classification, 137 adult patients with OSHAS were diagnosed as REM-related OSAHS [REM apnea hyponea index (AHI)/NREM AHI > 1] or NREM-related OSAHS (REM AHI/NREM AHI < 1).Polysonmographic data were compared and discussed.Results ①There were 72 cases defined as REM-related OSAHS (52.6％) and 65 cases defined as NREM-related OSAHS (47.4％).②In all cases, total AHI and NREM AHI in REM-related OSAHS were significantly lower than those in NREM-related OSAHS, while lowest arterial oxygen saturation (LSaO_2), REM LSaO_2 and NREM LSaO_2 were significandy higher than those in NREM-related OSAHS (t were - 6.466, - 7.638, 3.426, 2.472, 4.873 respectively, P < 0.05).No significance was found in sleep structure, REM AHI and REM LSaO_2 between REM-related and NREM-related OSAHS (P > 0.05).③Given the severity of OSHAS, the constituent ratio of REM-related OSAHS decreased (77.8％ ,61.5％, 37.3％) from mild to severe OSAHS, while that of NREM-related OSAHS rose (22.7％ ,38.5％ ,62.7％ ; X~2 = 16.996, P < 0.01). In mild and moderate groups, REM LSaO_2 of REM-related OSAHS was significantly lower than those in NREM-related OSAHS (t were -4.273 and -2.136, P < 0.05), while the differences of total AHI and LSaO_2 ,NREM LSaO_2 between these two types were not significant.In severe group, AHI in NREM-related OSAHS was significantly higher than that in REM-related OSAHS, while LSaO_2,REM LSaO_2 and NREM LSaO_2 was significantly lower than those in REM-related OASHS (t were -4.943, 2.574, 1.996, 3.571, P≤0.05).④There was no significance in sleeping latency and efficiency between REM-related and NREM-related OSHAS.Conclusions REM-related OSHAS mainly exists in mild and moderate OSHAS, while NREM-related one mainly exists in severe OSHAS.NREM-related OSAHS may be more severe in AHI and hypoxia than REM-related one.Whenever obstructive apnea happened in REM or NREM period, its impacts on sleep structure, efficiency and latency have no difference.
