Diagnosis and treatment of cervical Castleman disease presenting as a neck mass.
- Author:
Jun WANG
1
;
Wei-hong XIN
;
Yu-xin SUN
;
Qian-qian CHEN
;
Cui-da MENG
;
Jian YUE
;
Ying-nan KAN
;
Jia-jing ZHU
;
Zhan-quan YANG
;
Ping YAO
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Castleman Disease; diagnosis; pathology; Female; Humans; Lymph Nodes; pathology; Male; Middle Aged; Neck; pathology; Retrospective Studies; Young Adult
- From: Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2010;45(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical and pathological features, diagnosis and treatment of Castleman disease (CD).
METHODSClinical features and related information on diagnosis and treatment of eight cases of CD were retrospectively analyzed. The size of involved lymph nodes ranged from (2 cm x 2 cm x 3 cm) - (4 cm x 3 cm x 2 cm). The lymph nodes were found in level I (1 case), level II (3 cases), level III (3 cases) and level IV (1 case). CT examination in eight patients showed the lesions manifested as ellipse soft masses. Dynamic contrast CT scan in four patients showed ring-enhanced area around the masses. Blood routine examination in eight patients were generally normal, with six patients had mild anemia.
RESULTSBased on the clinical classification, all lesions in this group were localized CD. Histopathology indicated that all lesions were of hyaline-vascular type. After surgery, there was no recurrence during the follow-up period.
CONCLUSIONSPatients with localized CD mainly have lymphadenectasis in a single location. The CT scan can give some evidence. Surgery should be given first priority.
