Diagnosis and treatment of cervical Castleman disease presenting as a neck mass
10.3760/cma.j.issn.1673-0860.2010.02.007
- VernacularTitle:以颈部淋巴结肿大为首发症状的局灶型Castleman病诊治体会
- Author:
Jun WANG
1
;
Wei-Hong XIN
;
Yu-Xin SUN
;
Qian-Qian CHEN
;
Cui-Da MENG
;
Jian YUE
;
Ying-Nan KAN
;
Jia-Jing ZHU
;
Zhan-Quan YANG
;
Ping YAO
Author Information
1. 吉林大学中日联谊医院
- Keywords:
Giant lymph node hyperplasia;
Lymph node excision;
Neck
- From:
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
2010;45(2):116-119
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological features, diagnosis and treatment of Castleman disease (CD).Methods Clinical features and related information on diagnosis and treatment of eight cases of CD were retrospectively analyzed.The size of involved lymph nodes ranged from (2 cm×2 cm×3 cm)-(4 cm×3 cm×2 cm).The lymph nodes were found in level Ⅰ (1 case), level Ⅱ (3cases) ,level Ⅲ (3 cases) and level Ⅳ (1 case).CT examination in eight patients showed the lesions manifested as ellipse soft masses.Dynamic contrast CT scan in four patients showed ring-enhanced area around the masses.Blood routine examination in eight patients were generally normal, with six patients had mild anemia.Results Based on the clinical classification, all lesions in this group were localized CD.Histopathology indicated that all lesions were of hyaline-vascular type. After surgery, there was no recurrence during the follow-up period. ConclusionsPatients with localized CD mainly have lymphadenectasis in a single location.The CT scan can give some evidence.Surgery should be given first priority.